Peggy Biga
Research Interests
Organismal growth biology and physiology – mostly using fishes as models and comparative genomic, epigenomic, molecular, and cell biology approaches.
Current funded projects
1. Maternal dietary effects on offspring growth and metabolic physiology. USDA-NIFA 2023-67016-39339
2. Mechanisms of sex-specific aging phenotypes across the animal kingdom. NSF-BII DBI-2213824 (https://iisage.org)
Selected Publications
1. P.R. Biga*, J.E. Duan*, T.E. Young*, J.R. Marks*, A. Bronikowski*, L.P. Decena*, E.C. Randolph*, A.G. Pavuluri*, G. Li*, Y. Fang*, G.S. Wilkinson*, G. Singh, N.T. Nigrin, E.N. Larschan, A.J. Lonski, and N.C. Riddle. 2024. Hallmarks of Aging: A User’s Guide for Comparative Biologists. Ageing Research Reviews, 104:102616 *Co-first authors. https://doi.org/10.1016/j.arr.2024.102616
2. Freij, K.W., B.M. Cleveland, and P.R. Biga. 2024. Remodeling of the epigenetic landscape in rainbow trout, Oncorhynchus mykiss, offspring in response to maternal choline intake. In review: Comparative Biochemistry and Physiology, Part D. Genomics and Proteomics. https://doi.org/10.1016/j.cbd.2024.101348
3. Reid, R.M., S. Turkmen, B.M. Cleveland, and P.R. Biga. 2024. Direct actions of growth hormone in rainbow trout, Oncorhynchus mykiss, skeletal muscle cells in vitro. Comp. Biochem. and Phys., Part A. Mol. and Int. Phys. 297:111725. https://doi.org/10.1016/j.cbpa.2024.111725
4. Freij, K.W., B. Cleveland, and P.R. Biga. 2024. Maternal dietary choline levels cause transcriptome shifts due to genotype-by-diet interactions in rainbow trout (Oncorhynchus mykiss). Comp. Biochem. Phys. D. Genomics and Proteomics. doi:10.1016/j.cbd.2024.101193
5. Riddle, N.C., P.R. Biga, A.M. Bronikowski, J.R. Walters, G.S. Wilkinson, and IISAGE Consortium. 2023. Comparative analysis of animal lifespan. GeroScience. https://doi.org/10.1007/s11357-023-00984-2
6. Hogg, D.W., A.L. Reid, T.L. Dodsworth, Y. Chen, R.M. Reid, M. Xu, M. Husic, P.R. Biga, A. Slee, L.T. Buck, D. Barsyte-Lovejoy, M. Locke, and D.A. Lovejoy. 2022. Skeletal muscle metabolism and contraction performance regulation by teneurin C-terminal-associated peptide-1. Front. Physiol. 13:1031264. doi: 10.3389/fphys. 2022.1031264
7. Bronikowski, A. M., Meisel, R. P., Biga, P. R., Walters, J. R., Mank, J. E., Larschan, E., Wilkinson, G. S., Valenzuela, N., Conard, A. M., de Magalhães, J. P., Duan, J., Elias, A. E., Gamble, T., Graze, R. M., Gribble, K. E., Kreiling, J. A., and Riddle, N. C. (2021). Sex-specific aging in animals: Perspective and future directions. Aging Cell, 00, e13542. https://doi.org/10.1111/acel.13542
8. Reid, R.M., A.L. Reid, D.A. Lovejoy, and P.R. Biga. 2021. Teneurin C-Terminal Associated Peptide (TCAP)-3 Increases Metabolic Activity in Zebrafish. Frontiers in Marine Science. 7. Doi: 10.3389/fmars.2020.591160
9. Cleveland, B.M., T.D. Leeds, M.J. Picklo, C. Brentesen, J. Frost, and P.R. Biga. 2020. Supplementing rainbow trout (Oncorhynchus mykiss) broodstock diets with choline and methionine improves growth in offspring. Journal of the World Aquaculture Society. 1-16. Doi: 10.1111/jwas.12634
10. Latimer, M.N., R.M. Reid, P.R. Biga, and B.M. Cleveland. 2019. Glucose regulates protein turnover and growth-related mechanisms in rainbow trout myogenic precursor cells. Comp. Biochem. Physiol. A. 232:91-97. Doi:10.1016/j.cbpa. 2019.03.010. PMID: 30904682
Please see faculty member’s CV or website for a complete list of publications and additional information.